Thermo Scientific™ TheraPure™ 2'-MOE-A Phosphoramidite, serum vial bottle

Code produit. 18054070

Marque: Thermo Scientific™ 27101902

Description

2'-MOE-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis.

2'-MOE-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methoxy-ethyl (MOE) protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methoxy-ethyl (MOE) modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.

Features:

• Full chemical name – 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N⁶-benzoyl-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula – C₅₀H₅₈N₇O₉P
• Base – A
• Base Protection – Bz
• Molecular weight – 932.03 g/mol
• CAS number – 251647-53-7
• HPLC purity – ≥99%; M-11 Impurity ≤0.01%
• ³¹P NMR purity – ≥99%

Spécification

• For Use With (Equipment): AKTA Synthesizers, Applied Biosystems Synthesizers
• Product Type: 2in-MOE-A CEP
• Content And Storage: Store in freezer (at or below -20°C).
• Nucleoside Type: Adenosine (A)
• Reagent Features: 2in-MOE modified
• Shipping Condition: Room Temperature
• Purity: 99%
• Quantity: 1 g
• Reagent Type: Phosphoramidite
• Grade: TheraPure™
• Nucleic Acid Type: RNA
• Product Line: TheraPure
• Form: Powder