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MedChemExpress 2-Methoxyestradiol

Product Code. 16491177
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50 mg
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Product Code. 16491177

Brand: MedChemExpress HY12033

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Description

MedChemExpress 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa.

Specifications

Content And Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Weight (g/mol) 302.41 g/mol
Shipping Condition Room temperature
For Use With (Application) Cancer-programmed cell death
CAS 362-07-2
Product Type Natural Products
Purity 96.96%
Solubility DMSO : ≥ 100 mg/mL (330.68 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Synonym 2-ME2∣ NSC-659853
Target Microtubule/Tubulin∣Reactive Oxygen Species∣Apoptosis∣Autophagy∣Endogenous Metabolite
Quantity 50 mg
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