2-Mercaptopyridine N-oxide, 99%

Product Code. 11408136

Brand: Thermo Scientific Alfa Aesar A14152.06

Description

CAS: 1121-31-9 | C5H5NOS | 127.161 g/mol

2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.

Solubility
Soluble in tris-hydrochloric acid.

Notes
Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 1121-31-9
• Molecular Formula: C5H5NOS
• Molecular Weight (g/mol): 127.161
• MDL Number: MFCD00006196
• InChI Key: YBBJKCMMCRQZMA-UHFFFAOYSA-N
• Synonym: pyrithione, 2-mercaptopyridine n-oxide, 2-mercaptopyridine-n-oxide, 1-hydroxy-2-pyridinethione, omadine, 2-pyridinethiol, 1-oxide, 1-hydroxyl-1h-pyridine-2-thione, n-hydroxypyridine-2-thione, 1-hydroxy-2 1h-pyridinethione, 2-pyridinethiol 1-oxide
• PubChem CID: 1570
• ChEBI: CHEBI:36578
• IUPAC Name: 1-hydroxypyridine-2-thione
• SMILES: C1=CC(=S)N(C=C1)O

• Melting Point: 69°C to 72°C
• Quantity: 5 g
• Beilstein: 906983
• Sensitivity: Air and light sensitive
• Merck Index: 14,7994
• Solubility Information: Soluble in tris-hydrochloric acid.
• Formula Weight: 127.17
• Percent Purity: 99%
• Chemical Name or Material: 2-Mercaptopyridine N-oxide

Safety and Handling

Product Identifier

• 2-Mercaptopyridine-N-oxide

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : 2-Mercaptopyridine-N-oxide

SDS

RUO – Research Use Only