2-Iodoacetamide, 98%, stab. with ca 5-8% water

Product Code. 11467736

Brand: Thermo Scientific Alfa Aesar A14715.06

Beschreibung

CAS: 144-48-9 | C2H4INO | 184.964 g/mol

Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Solubility
Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.

Notes
Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.

Spezifikation

Chemische Identifikatoren

• CAS: 144-48-9
• Molecular Formula: C2H4INO
• Molecular Weight (g/mol): 184.964
• MDL Number: MFCD00008028
• InChI Key: PGLTVOMIXTUURA-UHFFFAOYSA-N
• Synonym: iodoacetamide, monoiodoacetamide, surauto, acetamide, 2-iodo, 2-iodo-acetamide, usaf d-1, alpha-iodoacetamide, ccris 7710, unii-zrh8m27s79, n-3-methoxy-4-butoxybenzyl thiobarbituric acid
• PubChem CID: 3727
• IUPAC Name: 2-iodoacetamide
• SMILES: C(C(=O)N)I

• Melting Point: 92°C to 95°(dried)
• Assay Percent Range: 98%, stabilized with ca 5% water
• Quantity: 5 g
• UN Number: UN2811
• Beilstein: 1739080
• Sensitivity: Light sensitive
• Solubility Information: Soluble in water,dimethyl formamide and ethanol. Slightly soluble in methanol.
• Formula Weight: 184.96
• Percent Purity: 98%
• Chemical Name or Material: Iodoacetamide, stabilized with ≈5 to 8% water

Sicherheit und Handhabung

Sicherheitsdatenblatt (SDS)

RUO – Research Use Only