2-Hydroxyisobutyric acid, 99% (dry wt.), water <2%

Product Code.	Quantity	unitSize
11434524	25 g	25g
11444524	100 g	100g
11454524	500 g	500g

Product Code. 11434524 Supplier Thermo Scientific Alfa Aesar Supplier No. A13146.14

Description

CAS: 594-61-6 | C4H8O3 | 104.11 g/mol

2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.

Solubility
Soluble in water, ether, alcohol, methanol and hot benzene.

Notes
Incompatible with oxidizing agents, bases and reducing agents.

Specifications

Chemical Identifiers

• CAS: 594-61-6
• Molecular Formula: C4H8O3
• Molecular Weight (g/mol): 104.11
• MDL Number: MFCD00004459
• InChI Key: BWLBGMIXKSTLSX-UHFFFAOYSA-N
• Synonym: 2-hydroxyisobutyric acid, 2-methyllactic acid, acetonic acid, 2-hydroxy-2-methylpropionic acid, alpha-hydroxyisobutyric acid, hydroxydimethylacetic acid, acetonate, propanoic acid, 2-hydroxy-2-methyl, alpha-hydroxyisobutanoic acid, 2-hydroxyisobutyricacid
• PubChem CID: 11671
• ChEBI: CHEBI:50129
• IUPAC Name: 2-hydroxy-2-methylpropanoic acid
• SMILES: CC(C)(O)C(O)=O

• Melting Point: 77°C to 80°C
• Density: 1.24
• Boiling Point: 114°C (12 mmHg)
• Quantity: 25 g
• Beilstein: 1744739
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water,ether,alcohol,methanol and hot benzene.
• Formula Weight: 104.11
• Percent Purity: 99%
• Assay: (dry wt.), water <2%
• Chemical Name or Material: 2-Hydroxyisobutyric acid

Safety and Handling

Product Identifier

• 2-Hydroxyisobutyric acid

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H318-Causes serious eye damage.
• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contain: 2-Hydroxyisobutyricacid

SDS

RUO – Research Use Only