missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18013922

Tocris Bioscience™ 2-Deoxy-D-glucose

Product Code. 18013922
Click to view available options
Quantity:
50 mg
Unit Size:
50mg
This item is not returnable. View return policy

Product Code. 18013922

Brand: Tocris Bioscience™ 4515/50

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Non-metabolizable glucose analog; hexokinase substrate

2-Deoxy-D-glucose is a non-metabolizable glucose analog. Inhibits phosphorylation of glucose by hexokinase; causes depletion of cellular ATP. Also inhibits phosphoglucose isomerase (PGI) competitively. Causes cell cycle inhibition and cell death in in vitro models of hypoxia; blocks tumor cell growth in animal models. Also shown to induce the unfolded protein response (UPR). 2-Deoxy-D-glucose disrupts N-glycan expression on the surface of pancreatic adenocarcinoma cells. 2-Deoxy-D-glucose enhances chimeric antigen receptor T cell activity in different xenograft mouse models of pancreatic adenocarcinoma cells.
TRUSTED_SUSTAINABILITY

Specifications

CAS 154-17-6
Quantity 50 mg
Molecular Formula C6H12O5
Formula Weight 164.16
Purity >98%
Molecular Weight (g/mol) 164.16
Chemical Name or Material 2-Deoxy-D-glucose
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.