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  7. 2-Amino-4,6-dichloropyrimidine, 98%

2-Amino-4,6-dichloropyrimidine, 98%

Product Code. 11443734
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Product Code. 11443734

Brand: Thermo Scientific Alfa Aesar A11330.06

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Description

CAS: 56-05-3 | C4H3Cl2N3 | 163.989 g/mol

Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst.

Solubility
Insoluble in water, soluble in acetone, two monomer (VCM) and thermal toluene.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 56-05-3
Molecular Formula C4H3Cl2N3
Molecular Weight (g/mol) 163.989
MDL Number MFCD00006090
InChI Key JPZOAVGMSDSWSW-UHFFFAOYSA-N
Synonym 2-amino-4,6-dichloropyrimidine, 4,6-dichloro-2-pyrimidinamine, 2-pyrimidinamine, 4,6-dichloro, 4,6-dichloropyrimidin-2-ylamine, ccris 7460, 4,6-dichloro-pyrimidin-2-ylamine, pyrimidine, 2-amino-4,6-dichloro, 2-amino-4,6-dichloro pyrimidine, 4,6-dichloropyrimidine-2-ylamine, zlchem 351
PubChem CID 65522
IUPAC Name 4,6-dichloropyrimidin-2-amine
SMILES C1=C(N=C(N=C1Cl)N)Cl

Specifications

Melting Point 218°C to 222°C
Quantity 5 g
Beilstein 118454
Solubility Information Insoluble in water,soluble in acetone,two monomer (VCM) and thermal toluene.
Formula Weight 164
Percent Purity 98%
Chemical Name or Material 2-Amino-4,6-dichloropyrimidine

RUO – Research Use Only

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