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  8. (1S,3R,5R)-PIM447 dihydrochloride, MedChemExpress

(1S,3R,5R)-PIM447 dihydrochloride, MedChemExpress

Product Code. 16480188
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Product Code. 16480188 Supplier Medchem Express Supplier No. HY19322C

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Description

MedChemExpress (1S,3R,5R)-PIM447 (dihydrochloride) an PIM inhibitor extracted from patent US 20100056576 A1, compound example 72, has IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3.

(1S,3R,5R)-PIM447 (dihydrochloride) an PIM inhibitor extracted from patent US 20100056576 A1, compound example 72, has IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3.

Specifications

Chemical Name or Material (1S,3R,5R)-PIM447 dihydrochloride
Color Off-White
Purity Grade Notes Research
Molecular Formula C24H25Cl2F3N4O
Quantity 5 mg
Synonym (1S,3R,5R)-LGH447 dihydrochloride
Solubility Information DMSO : 33.33 mg/mL (64.92 mM; Need ultrasonic) ∣H2O : 12.5 mg/mL (24.35 mM; Need ultrasonic)
SMILES O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C([C@@H]4C[C@H](N)C[C@H](C)C4)C=CN=C3.Cl.Cl
Molecular Weight (g/mol) 513.38
Formula Weight 513.38
Percent Purity 98.13%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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