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Tocris Bioscience™ 17-AAG

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Quantity:
1 mg
Unit Size:
1mg
Description
Inhibitor of heat shock protein 90 (Hsp90) chaperone activity, and an analog of geldanamycin (Cat. No. 1368). Subsequently inhibits the activity of oncogenic proteins such as p185erbB-2 (IC50 = 31 nM), N-ras, Ki-ras and c-Akt. Antitumor in vivo. Also protects neuroprogenitor cells against stress-induced apoptosis at low concentrations (10 nM) in vitro.
Specifications
Specifications
| CAS | 75747-14-7 |
| Quantity | 1 mg |
| Molecular Formula | C31H43N3O8 |
| Formula Weight | 585.7 |
| Purity | >98% |
| Molecular Weight (g/mol) | 585.698 |
| Chemical Name or Material | 17-AAG |
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