14-3-3 epsilon Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11648-2-AP-20UL

Product Code. 16838873

Description

This antibody was raised against full-length 14-3-3 epsilon.

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

Specifications

• Antigen: 14-3-3 epsilon
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: YWHAE
• Gene Alias: 14 3 3 protein epsilon, 14 3 3E, 14-3-3, 14-3-3 epsilon, KCIP 1, MDCR, MDS, YWHAE
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22627, 29753, 7531
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Immunofluorescence, Flow Cytometry, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P62258, P62259, P62260
• Gene Symbols: YWHAE
• Immunogen: 14-3-3 epsilon Fusion Protein Ag2247
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Mouse
• Product Type: Antibody
• Isotype: IgG