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Tocris Bioscience™ ML 347

Product Code. 18788617
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10 mg
50 mg
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50mg
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18788617 10 mg 10mg
18725718 50 mg 50mg
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Product Code. 18788617 Supplier Tocris Bioscience™ Supplier No. 4945/10

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161.50 GBP valid until 2026-03-31
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Description

Potent and selective ALK1 and ALK2 inhibitor

ML 347 is a potent and selective ALK2 and ALK1 inhibitor (IC50 values are 32 and 46 nM, respectively); displays >200 fold selectivity over ALK3 and ALK6 and >400 fold selectivity over VEGF2. Exhibits no activity at ALK4, ALK5 or in a panel of related kinases. Inhibits BMP4 signaling in a functional assay (IC50 = 152 nM).
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type ML 347
Purity >98%
Molecular Weight (g/mol) 352.39
Inhibitors ML 347

For Research Use Only

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