Invitrogen™ CNGA4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5145067

Product Code. 18056151

Description

Immunogen sequence: LLAELESSAL KIAYRIERLE WQTREWPMPE DLAEADDEGE PEEGTSKDEE GRAS Antigen sequence identity: Mouse 83%; Rat 87%.

Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.

Specifications

• Antigen: CNGA4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CNGA4
• Gene Alias: Cgn2; CNCA2; CNCalpha4, CNG5; cng channel; CNG channel alpha-4; CNG4; CNG-4; CNG5; CNGA4; CNGB2; cyclic nucleotide gated cation channel; cyclic nucleotide gated channel alpha 4; cyclic nucleotide gated channel beta 2; cyclic nucleotide-gated cation channel alpha 4; cyclic nucleotide-gated cation channel alpha-4; Cyclic nucleotide-gated channel alpha-4; cyclic nucleotide-gated olfactory channel subunit OCNC2; OCNC2; OCNCb; OCNCBETA; olfactory cyclic nucleotide-gated channel; rOCNC2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1262
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8IV77
• Gene Symbols: CNGA4
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 514-567. Recombinant protein control fragment (Product #RP-109765).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid