1-Methylpiperazine, 98+%

Product Code.	Quantity	unitSize
11449802	2500 mL	2500mL
11429802	100 mL	100mL
11439802	500 mL	500mL

Product Code. 11449802 Supplier Thermo Scientific Alfa Aesar Supplier No. A10837.0F

Description

CAS: 109-01-3 | C5H12N2 | 100.165 g/mol

1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

Solubility
Miscible with water and methanol.

Notes
Hygroscopic. Moisture sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.

Spécification

Identifiants chimiques

• CAS: 109-01-3
• Molecular Formula: C5H12N2
• Molecular Weight (g/mol): 100.165
• MDL Number: MFCD00005966
• InChI Key: PVOAHINGSUIXLS-UHFFFAOYSA-N
• Synonym: n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine
• PubChem CID: 53167
• IUPAC Name: 1-methylpiperazine
• SMILES: CN1CCNCC1

• Melting Point: -6°C
• Density: 0.903
• Boiling Point: 137°C to 139°C
• Flash Point: 34°C (93°F)
• Odor: Amine-like
• Refractive Index: 1.4655
• Quantity: 2500 mL
• UN Number: UN2734
• Beilstein: 102724
• Sensitivity: Air Sensitive
• Solubility Information: Miscible with water and methanol.
• Formula Weight: 100.17
• Percent Purity: ≥98%
• Chemical Name or Material: 1-Methylpiperazine

Sécurité et traitement

FDS

RUO – Research Use Only