1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%, Thermo Scientific Chemicals

Description

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.

Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.

Specifications

• Melting Point: ∼113°C
• Linear Formula: CH₃CH₂N=C=N(CH₂)₃N(CH₃)₂·HCl
• Quantity: 25 g
• Beilstein: 5764110
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in acetonitrile dichloromethane,dimethylformamide,and tetrahydrofuran. Slightly soluble in water.
• Formula Weight: 191.7
• Percent Purity: ≥98%
• Chemical Name or Material: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride

Safety and Handling

Product Identifier

• 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride

Signal Word

• Warning

Hazard Category

• Skin corrosion/irritation Category 2
• Serious eye damage/eye irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P405-Store locked up.
• P501-Dispose of contents/container to .

RUO – Research Use Only