CAS RN 901119-35-5

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Fostamatinib, TRC

CAS: 901119-35-5 Molecular Formula: C23H26FN6O9P Molecular Weight (g/mol): 580.47 Synonym: R 788,6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one SMILES: COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)N(COP(=O)(O)O)c4n3)n2)cc(OC)c1OC

Pricing and Availability
Specifications

CAS	901119-35-5
Molecular Weight (g/mol)	580.47
SMILES	COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)N(COP(=O)(O)O)c4n3)n2)cc(OC)c1OC
Synonym	R 788,6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one
Molecular Formula	C23H26FN6O9P

Fostamatinib, MedChemExpress

MedChemExpress Fostamatinib (R788) is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	580.46
Color	White
Physical Form	Solid
Chemical Name or Material	Fostamatinib
Grade	Research
SMILES	COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O)(O)=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.61%
CAS	901119-35-5
Solubility Information	DMSO : 62.5 mg/mL (107.67 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Synonym	R788
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₂₆FN₆O₉P
Formula Weight	580.46

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