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CAS RN 86639-52-3

H3CNONHO(S)HOH3COO

CAS RN 86639-52-3

IUPAC Name: (19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Synonyms: 7-ethyl-10-hydroxy-captothecin
Molecular Weight (g/mol): 392.41
Molecular Formula: C22H20N2O5
InChi Key: FJHBVJOVLFPMQE-QFIPXVFZSA-N
SMILES: CCC1=C2C=C(O)C=CC2=NC2=C1CN1C2=CC2=C(COC(=O)[C@]2(O)CC)C1=O
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7-Ethyl-10-hydroxycamptothecin, 98%

CAS: 86639-52-3 Molecular Formula: C22H20N2O5 Molecular Weight (g/mol): 392.4 InChI Key: FJHBVJOVLFPMQE-QFIPXVFZSA-N Synonym: 7-ethyl-10-hydroxycamptothecin,sn 38 lactone,7-ethyl-10-hydroxy-camptothecin,10-hydroxy-7-ethylcamptothecin,7-ethyl-10-hydroxycamptothecine,le-sn38,7-ethyl-10-hydroxy-20 s-camptothecin,captothecin, 7-ethyl-10-hydroxy,s-4,11-diethyl-4,9-dihydroxy-1h-pyrano 3',4':6,7 indolizino 1,2-b quinoline-3,14 4h,12h-dione,7-ethyl-10-hydroxy camptothecin PubChem CID: 104842 ChEBI: CHEBI:8988 SMILES: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O

PubChem CID 104842
CAS 86639-52-3
Molecular Weight (g/mol) 392.4
ChEBI CHEBI:8988
SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Synonym 7-ethyl-10-hydroxycamptothecin,sn 38 lactone,7-ethyl-10-hydroxy-camptothecin,10-hydroxy-7-ethylcamptothecin,7-ethyl-10-hydroxycamptothecine,le-sn38,7-ethyl-10-hydroxy-20 s-camptothecin,captothecin, 7-ethyl-10-hydroxy,s-4,11-diethyl-4,9-dihydroxy-1h-pyrano 3',4':6,7 indolizino 1,2-b quinoline-3,14 4h,12h-dione,7-ethyl-10-hydroxy camptothecin
InChI Key FJHBVJOVLFPMQE-QFIPXVFZSA-N
Molecular Formula C22H20N2O5
2
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Tocris Bioscience™ SN 38
GREENER_CHOICE

CAS: 86639-52-3 Molecular Formula: C22H20N2O5

CAS 86639-52-3
Molecular Formula C22H20N2O5
3

7-Ethyl-10-hydroxycamptothecin ((S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione), Mikromol™

Discover Mikromol - your trusted source for high-quality pharmaceutical reference standards. Supporting accurate, compliant analysis with ISO 17034-accredited materials designed for confidence in every result.

4

SN-38, TRC

CAS: 86639-52-3 Molecular Formula: C22 H20 N2 O5 Molecular Weight (g/mol): 392.4 Synonym: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (4S)-,(S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,10-Hydroxy-7-ethylcamptothecin,7-Ethyl-10-hydroxy-20(S)-camptothecin,7-Ethyl-10-hydroxycamptothecin,(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,11-Ethyl-9-hydroxycamptothecin,SN-38 IUPAC Name: (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione SMILES: CCc1c2CN3C(=O)C4=C(C=C3c2nc5ccc(O)cc15)[C@@](O)(CC)C(=O)OC4

CAS 86639-52-3
Molecular Weight (g/mol) 392.4
SMILES CCc1c2CN3C(=O)C4=C(C=C3c2nc5ccc(O)cc15)[C@@](O)(CC)C(=O)OC4
Synonym 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4,9-dihydroxy-, (4S)-,(S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,10-Hydroxy-7-ethylcamptothecin,7-Ethyl-10-hydroxy-20(S)-camptothecin,7-Ethyl-10-hydroxycamptothecin,(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,11-Ethyl-9-hydroxycamptothecin,SN-38
IUPAC Name (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Molecular Formula C22 H20 N2 O5
5

SN-38, MedChemExpress

MedChemExpress SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 392.4
Color White
Physical Form Solid
Chemical Name or Material SN-38
Grade Research
SMILES O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C2)=O
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.03%
CAS 86639-52-3
Solubility Information DMSO : 25 mg/mL (63.71 mM; Need ultrasonic)
Health Hazard 1 H301
Synonym NK012
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C22H20N2O5
Formula Weight 392.4