CAS RN 5852-78-8
CAS RN 5852-78-8
IUPAC Name:
8-hydroxyquinoline-5-carboxylic acid
Synonyms:
8-hydroxyquinoline-5-carboxylic acid
Molecular Weight (g/mol):
189.17
Molecular Formula:
C10H7NO3
InChi Key:
JGRPKOGHYBAVMW-UHFFFAOYSA-N
SMILES:
OC(=O)C1=CC=C(O)C2=NC=CC=C12
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1
Tocris Bioscience™ IOX 1
CAS: 5852-78-8 Molecular Formula: C10H7NO3
2
IOX1, MedChemExpress
MedChemExpress IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively. IOX1 also inhibits ALKBH5.
