CAS RN 501010-06-6

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GGTI-2418, MedChemExpress

MedChemExpress GGTI-2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regression of breast tumors.

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Specifications

Molecular Weight (g/mol)	441.52
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	GGTI-2418
Grade	Research
SMILES	CC(C)C[C@@H](C(O)=O)NC(N1[C@@H](CC2=CC=CC=C2)C(N(CC3=C(C)N=CN3)CC1)=O)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.04%
CAS	501010-06-6
Solubility Information	DMSO : 125 mg/mL (283.11 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₃₁N₅O₄
Formula Weight	441.52

CAS RN 501010-06-6

CAS RN 501010-06-6

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