CAS RN 315703-52-7

IUPAC Name: N-(4-ethoxyphenyl)-4-{2-methylimidazo[1,2-a]pyridin-3-yl}-1,3-thiazol-2-amine

Synonyms: N-(4-ethoxyphenyl)-4-{2-methylimidazo[1,2-a]pyridin-3-yl}-1,3-thiazol-2-amine

Molecular Weight (g/mol): 350.44

Molecular Formula: C19H18N4OS

InChi Key: ROYXIPOUVGDTAO-UHFFFAOYSA-N

SMILES: CCOC1=CC=C(NC2=NC(=CS2)C2=C(C)N=C3C=CC=CN23)C=C1

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MedChemExpress JK184 is a potent Hedgehog (Hh) pathway inhibitor with IC50 of 30 nM in mammalian cells.

Molecular Weight (g/mol)	350.44
Color	Pink
Physical Form	Solid
Chemical Name or Material	JK184
Grade	Research
SMILES	CC1=C(C2=CSC(NC3=CC=C(OCC)C=C3)=N2)N4C=CC=CC4=N1
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.37%
CAS	315703-52-7
Solubility Information	DMSO : ≥ 50 mg/mL (142.68 mM)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₈N₄OS
Formula Weight	350.44