CAS RN 301836-43-1

IUPAC Name: 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide

Synonyms: 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide

Molecular Weight (g/mol): 398.42

Molecular Formula: C23H18N4O3

InChi Key: DPDZHVCKYBCJHW-UHFFFAOYSA-N

SMILES: NC(=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=CC=N1)C1=CC2=C(OCCO2)C=C1

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CAS: 301836-43-1 Molecular Formula: C23H18N4O3

CAS	301836-43-1
Molecular Formula	C23H18N4O3

MedChemExpress D4476 is a potent, selective and cell-permeable inhibitor of casein kinase 1(CK1) with an IC50 value of 0.3 μM in vitro.

Molecular Weight (g/mol)	398.41
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	D4476
Grade	Research
SMILES	O=C(N)C1=CC=C(C=C1)C(N2)=NC(C3=CC=C4OCCOC4=C3)=C2C5=NC=CC=C5
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.14%
CAS	301836-43-1
Solubility Information	DMSO : ≥ 50 mg/mL (125.50 mM)
Synonym	Casein Kinase I Inhibitor
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₁₈N₄O₃
Formula Weight	398.41

Activin/NODAL/TGF-β pathway inhibitor; Inhibits CK1, ALK5 and p38 MAPK