CAS RN 231277-92-2
CAS RN 231277-92-2
IUPAC Name:
N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine
Synonyms:
lapatinib tykerb lapatinib ditosylate tycerb C29H26ClFN4O4S lapatinib tosilate hydrate FMM
Molecular Weight (g/mol):
581.06
Molecular Formula:
C29H26ClFN4O4S
InChi Key:
BCFGMOOMADDAQU-UHFFFAOYSA-N
SMILES:
CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC=C2N=CN=C(NC3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)C2=C1
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Tocris Bioscience™ Lapatinib
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor (IC50 values are 9.8 and 10.2 nM, respectively)
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Lapatinib, MedChemExpress
MedChemExpress Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.
