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CAS RN 1799753-84-6

CAS RN 1799753-84-6

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Tocris Bioscience™ BAY 876

Potent and selective GLUT1 inhibitor

2

Tocris Bioscience™ BAY 876

Potent and selective GLUT1 inhibitor

3

BAY-876, MedChemExpress

MedChemExpress BAY-876 is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 496.42
Color White
Physical Form Solid
Chemical Name or Material BAY-876
Grade Research
SMILES O=C(C1=NC2=CC(F)=CC=C2C(C(NC3=C(C)N(CC4=CC=C(C#N)C=C4)N=C3C(F)(F)F)=O)=C1)N
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.0%
CAS 1799753-84-6
Solubility Information DMSO : ≥ 100 mg/mL (201.44 mM) ∣Methanol : 1 mg/mL (2.01 mM; ultrasonic and warming and heat to 60°C)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C24H16F4N6O2
Formula Weight 496.42