CAS RN 17692-51-2
CAS RN 17692-51-2
IUPAC Name:
(2R,4S,7R)-4-({[(benzyloxy)carbonyl]amino}methyl)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),9,12,14-tetraen-6-ium
Synonyms:
metergoline
Molecular Weight (g/mol):
404.53
Molecular Formula:
C25H30N3O2
InChi Key:
WZHJKEUHNJHDLS-QTGUNEKASA-O
SMILES:
CN1C=C2C[C@@H]3[C@H](C[C@@H](CNC(=O)OCC4=CC=CC=C4)C[NH+]3C)C3=C2C1=CC=C3
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Metergoline, MedChemExpress
MedChemExpress Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na+ channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation.
