CAS RN 1661854-97-2

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TAS6417, MedChemExpress

MedChemExpress TAS6417 (CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC50 values ranging from 1.1-8.0 nM.

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Molecular Weight (g/mol)	396.44
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	TAS6417
Grade	Research
SMILES	NC1=C2C(N3C(C(C)=C[C@@H](C3)NC(C=C)=O)=C2C4=CC5=CC=CC=C5N=C4)=NC=N1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	97.63%
CAS	1661854-97-2
Solubility Information	DMSO : 22.73 mg/mL (57.34 mM; Need ultrasonic)
Synonym	CLN-081
Purity Grade Notes	Research
Recommended Storage	4°C, protect from light, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light, stored under nitrogen)
Shelf Life	4°C, protect from light, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light, stored under nitrogen)
Molecular Formula	C₂₃H₂₀N₆O
Formula Weight	396.44

CAS RN 1661854-97-2

CAS RN 1661854-97-2

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