CAS RN 1639422-97-1

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JH-VIII-157-02, MedChemExpress

MedChemExpress JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.

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Specifications

Molecular Weight (g/mol)	465.55
Color	Off-White
Physical Form	Solid
Chemical Name or Material	JH-VIII-157-02
Grade	Research
SMILES	O=C(N(C)C)CN1N=CC(C2=C(CC)C=C3C(C(C)(C)C(NC4=C5C=CC(C#N)=C4)=C5C3=O)=C2)=C1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.67%
CAS	1639422-97-1
Solubility Information	DMSO : ≥ 25 mg/mL (53.70 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₈H₂₇N₅O₂
Formula Weight	465.55

CAS RN 1639422-97-1

CAS RN 1639422-97-1

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