CAS RN 1558021-37-6

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TP0463518, MedChemExpress

MedChemExpress TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM.

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Specifications

Molecular Weight (g/mol)	431.83
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	TP0463518
Grade	Research
SMILES	ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	98.02%
CAS	1558021-37-6
Solubility Information	DMSO : ≥ 125 mg/mL (289.47 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₁₈ClN₃O₆
Formula Weight	431.83

CAS RN 1558021-37-6

CAS RN 1558021-37-6

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