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CAS RN 154447-36-6

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CAS RN 154447-36-6

IUPAC Name: 2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one
Synonyms: 2-(morpholin-4-yl)-8-phenylchromen-4-one
Molecular Weight (g/mol): 307.35
Molecular Formula: C19H17NO3
InChi Key: CZQHHVNHHHRRDU-UHFFFAOYSA-N
SMILES: O=C1C=C(OC2=C(C=CC=C12)C1=CC=CC=C1)N1CCOCC1
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1

LY 294002, TRC

CAS: 154447-36-6 Chemical Name or Material: LY 294002 InChI Formula: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2 Molecular Formula: C19H17NO3 Molecular Weight (g/mol): 307.34 Recommended Storage: -20°C SMILES: COC(=O)C[C@@H](Br)C(=O)OC Synonym: NSC 697286,SF 1101,8-Phenyl-2-(morpholin-4-yl)-chromen-4-one,2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one,2-Morpholino-8-phenyl-4H-chromen-4-one

CAS 154447-36-6
Molecular Weight (g/mol) 307.34
InChI Formula InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
Chemical Name or Material LY 294002
Synonym NSC 697286,SF 1101,8-Phenyl-2-(morpholin-4-yl)-chromen-4-one,2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one,2-Morpholino-8-phenyl-4H-chromen-4-one
SMILES COC(=O)C[C@@H](Br)C(=O)OC
Recommended Storage -20°C
Molecular Formula C19H17NO3
2

LY294002, MedChemExpress

MedChemExpress LY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 μM for PI3Kα, PI3Kδ and PI3Kβ, respectively. LY294002 also inhibits CK2 with an IC50 of 98 nM. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC50 of 1.4 μM. LY294002 is an apoptosis activator.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 307.34
Color White
Physical Form Solid
Chemical Name or Material LY294002
Grade Research
SMILES O=C1C=C(OC2=C1C=CC=C2C3=CC=CC=C3)N4CCOCC4
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.0%
CAS 154447-36-6
Solubility Information DMSO : 50 mg/mL (162.69 mM; Need ultrasonic) ∣Ethanol : 50 mg/mL (162.69 mM; Need ultrasonic)
Health Hazard 1 H302∣H315∣H319∣H332∣H335
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C19H17NO3
Formula Weight 307.34
3

STEMCELL Technologies LY294002

PI3K/AKT pathway inhibitor; Inhibits PI3K

ENCOMPASS_PREFERRED
CAS 154447-36-6
Purity ≥98%
Molecular Formula C19H17NO3