CAS RN 1352066-68-2

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Navtemadlin, MedChemExpress

MedChemExpress Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	568.55
Color	White
Physical Form	Powder
Chemical Name or Material	Navtemadlin
Grade	Research
SMILES	O=C(O)C[C@]1(C)C(N([C@H](CS(=O)(C(C)C)=O)C(C)C)[C@H](C2=CC=C(Cl)C=C2)[C@@H](C3=CC=CC(Cl)=C3)C1)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	96.04%
CAS	1352066-68-2
Solubility Information	DMSO : ≥ 50 mg/mL (87.94 mM) ∣H2O : ≥ 0.1 mg/mL (0.18 mM)
Synonym	AMG 232 KRT-232
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended.
Molecular Formula	C₂₈H₃₅Cl₂NO₅S
Formula Weight	568.55

CAS RN 1352066-68-2

CAS RN 1352066-68-2

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