CAS RN 1351636-18-4

IUPAC Name: —

Synonyms: —

Molecular Weight (g/mol): —

Molecular Formula: —

InChi Key: —

SMILES: —

Grade

Molecular Weight (g/mol)

Percent Purity

Physical Form

Quantity

1 – 1 of 1 results

Tirabrutinib, MedChemExpress

MedChemExpress Tirabrutinib (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	454.48
Color	White
Physical Form	Solid
Chemical Name or Material	Tirabrutinib
Grade	Research
SMILES	O=C1N(C2=CC=C(OC3=CC=CC=C3)C=C2)C4=C(N)N=CN=C4N1[C@H]5CN(C(C#CC)=O)CC5
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.14%
CAS	1351636-18-4
Solubility Information	DMSO : ≥ 100 mg/mL (220.03 mM)
Health Hazard 1	H315∣H319∣H335
Synonym	ONO-4059 GS-4059
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₅H₂₂N₆O₃
Formula Weight	454.48

CAS RN 1351636-18-4

CAS RN 1351636-18-4

Filtered Search Results

Narrow Results