CAS RN 1206161-97-8
CAS RN 1206161-97-8
IUPAC Name:
N-(5-{4-[(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)methyl]phenyl}-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide
Synonyms:
filgotinib
Molecular Weight (g/mol):
425.51
Molecular Formula:
C21H23N5O3S
InChi Key:
RIJLVEAXPNLDTC-UHFFFAOYSA-N
SMILES:
O=C(NC1=NN2C(C=CC=C2C2=CC=C(CN3CCS(=O)(=O)CC3)C=C2)=N1)C1CC1
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GLPG-0634 (Filgotinib), TRC
CAS: 1206161-97-8 Molecular Formula: C21H23N5O3S Molecular Weight (g/mol): 425.5 Synonym: N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-Cyclopropanecarboxamide; IUPAC Name: N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide SMILES: CCCCCC(=O)Oc1ccc(cc1)C2C(=O)c3c(cc(O)cc3)OC=2
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Filgotinib, MedChemExpress
MedChemExpress Filgotinib (GLPG0634) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
