CAS RN 1138549-36-6

IUPAC Name: —

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Molecular Weight (g/mol): —

Molecular Formula: —

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Grade

Molecular Weight (g/mol)

Percent Purity

Physical Form

Quantity

MedChemExpress CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively.

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Specifications

Molecular Weight (g/mol)	513.61
Color	Off-White
Physical Form	Solid
Chemical Name or Material	CX-5461
Grade	Research
SMILES	CC1=NC=C(CNC(C2=C3N(C4=NC(N5CCN(CCC5)C)=CC=C4C2=O)C6=C(S3)C=CC=C6)=O)N=C1
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.0%
CAS	1138549-36-6
Solubility Information	DMSO : 2 mg/mL (3.89 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₇N₇O₂S
Formula Weight	513.61

CAS RN 1138549-36-6

CAS RN 1138549-36-6

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