CAS RN 1123838-51-6

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Glesatinib hydrochloride, MedChemExpress

MedChemExpress Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC).

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Specifications

Molecular Weight (g/mol)	656.17
Color	Pink
Physical Form	Solid
Chemical Name or Material	Glesatinib hydrochloride
Grade	Research
SMILES	O=C(NC(NC1=CC=C(OC2=C3C(C=C(C4=NC=C(CNCCOC)C=C4)S3)=NC=C2)C(F)=C1)=S)CC5=CC=C(F)C=C5.Cl
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	1123838-51-6
Solubility Information	DMSO : 50 mg/mL (76.20 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Synonym	MGCD265 hydrochloride
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₃₁H₂₈ClF₂N₅O₃S₂
Formula Weight	656.17

CAS RN 1123838-51-6

CAS RN 1123838-51-6

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