CAS RN 1095173-27-5

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Glasdegib, MedChemExpress

MedChemExpress Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM.

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Molecular Weight (g/mol)	374.44
Color	White
Physical Form	Powder
Chemical Name or Material	Glasdegib
Grade	Research
SMILES	O=C(NC1=CC=C(C#N)C=C1)N[C@H]2C[C@H](C3=NC4=CC=CC=C4N3)N(C)CC2
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.36%
CAS	1095173-27-5
Solubility Information	DMSO : ≥ 83.33 mg/mL (222.55 mM)
Synonym	PF-04449913
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₂₂N₆O
Formula Weight	374.44

CAS RN 1095173-27-5

CAS RN 1095173-27-5

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