Crosslinking Reagents

Reagents containing reactive end groups that respond to the presence of specific functional groups by forming bonds between polymer chains. Ideal for various applications including conjugation reactions, biomolecule labeling, and molecular purification.

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Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format

Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.

Pricing and Availability
Specifications

Shipping Condition	Ambient
Content And Storage	Upon receipt store desiccated at -20°C.
Description	Sulfo-SMCC
Cleavable	No
Water Soluble	Yes
Molecular Weight (g/mol)	436.37
Solubility	Water
Labeling Method	Chemical Labeling
Crosslinker Type	Heterobifunctional
Chemical Reactivity	Amine-Sulfhydryl
Cell Permeability	No
Format	Standard, Single-use, Premium-grade
Product Type	Crosslinker
Spacer	Short (<10 Å)
Reactive Moiety	Maleimide, Sulfo-NHS Ester
Spacer Arm Length	8.3 Å
PEGylated	No

Thermo Scientific™ Pierce™ DSG, No-Weigh™ Format

Pricing and Availability
Specifications

Cleavable	No
Water Soluble	No
Form	Powder
Molecular Weight (g/mol)	326.26
Solubility	DMF, DMSO
Labeling Method	Chemical Labeling
Crosslinker Type	Homobifunctional
Chemical Reactivity	Amine-Amine
Cell Permeability	Yes
Format	Standard, Single-use
Product Type	Crosslinker
Spacer	Short (<10 Å)
Reactive Moiety	NHS Ester
Spacer Arm Length	7.7 Å
PEGylated	No

Thermo Scientific™ Pierce™ Controlled Protein-Protein Crosslinking Kit

Chemically conjugate any two purified proteins (antibodies, enzymes, carriers, etc.) using sulfo-SMCC crosslinker, a complete kit with modification reagents and buffers.

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Crosslinking Reagents

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