Aminophenols

Organic compounds that consist of a phenol ring with an amino functional group substitution; amino functional groups consist of a nitrogen atom bonded to hydrogen atoms via single bonds.

MedChemExpress JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	297.31
Color	Gray
Physical Form	Solid
Chemical Name or Material	JANEX-1
Grade	Research
SMILES	OC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.6%
CAS	202475-60-3
Solubility Information	DMSO : ≥ 100 mg/mL (336.35 mM)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	WHI-P131 Jak3 inhibitor I
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₆H₁₅N₃O₃
Formula Weight	297.31

Aminophenols

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