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Phenylacetic acids

Organic compounds that consist of a phenyl group with a carboxylic acid group substitution; a carboxylic acid contains a carbon atom bonded to both a carbonyl group and a hydroxyl group.
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1 – 4 of 4 results
1

AM095 free acid, MedChemExpress

MedChemExpress AM095 (free acid) is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 456.49
Color Off-White
Physical Form Solid
Chemical Name or Material AM095 free acid
Grade Research
SMILES O=C(O)CC1=CC=C(C2=CC=C(C3=C(NC(O[C@@H](C4=CC=CC=C4)C)=O)C(C)=NO3)C=C2)C=C1
For Use With (Application) COVID-19-immunoregulation
Percent Purity 98.07%
CAS 1228690-36-5
Solubility Information DMSO : 67.3 mg/mL (147.43 mM; Need ultrasonic and warming)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C27H24N2O5
Formula Weight 456.49
2

RGX-104, MedChemExpress

MedChemExpress RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 596.08
Color White
Physical Form Solid
Chemical Name or Material RGX-104
Grade Research
SMILES O=C(O)CC1=CC=CC(OCC[C@H](N(CC2=CC=CC(C(F)(F)F)=C2Cl)CC(C3=CC=CC=C3)C4=CC=CC=C4)C)=C1
For Use With (Application) Cancer-programmed cell death
Percent Purity 99.35%
CAS 610318-54-2
Solubility Information DMSO : 100 mg/mL (167.76 mM; Need ultrasonic)
Health Hazard 1 H302∣H315∣H319∣H335
Purity Grade Notes Research
Recommended Storage 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula C34H33ClF3NO3
Formula Weight 596.08
3

Felbinac, MedChemExpress

MedChemExpress Felbinac is a potent non-steroidal anti-inflammatory agent, used to treat muscle inflammation and arthritis.

ENCOMPASS_PREFERRED
4

AM211, MedChemExpress

MedChemExpress AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 500.51
Color White
Physical Form Solid
Chemical Name or Material AM211
Grade Research
SMILES O=C(O)CC1=CC(C2=CC=C(C(F)(F)F)C=C2CN(CC)C(NCC3=CC=CC=C3)=O)=C(OC)C=C1
For Use With (Application) COVID-19-immunoregulation
Percent Purity 98.11%
CAS 1175526-27-8
Solubility Information DMSO : ≥ 125 mg/mL (249.75 mM)
Synonym AM211 free acid
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C27H27F3N2O4
Formula Weight 500.51