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Phenoxy compounds

Organic compounds that have one or more phenyl groups that are bonded to an oxygen with a radical electron; includes compounds with additional substitutions.

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J-147, MedChemExpress

MedChemExpress J-147 is an exceptionally potent, orally active, neuroprotective agent for cognitive enhancement. J-147 can readily pass the blood brain barrier (BBB). J-147 can inhibit monoamine oxidase B (MAO B) and the dopamine transporter with EC50 values of 1.88 μM and 0.649 μM, respectively. J-147 has potential for the treatment of Alzheimer’s disease (AD).

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 350.34
Color Pink
Physical Form Solid
Chemical Name or Material J-147
Grade Research
SMILES O=C(N(C1=CC=C(C)C=C1C)/N=C/C2=CC=CC(OC)=C2)C(F)(F)F
For Use With (Application) Neuroscience-Neurodegeneration
Percent Purity 95.0%
CAS 1146963-51-0
Solubility Information DMSO : ≥ 100 mg/mL (285.44 mM)
Health Hazard 1 H302
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C18H17F3N2O2
Formula Weight 350.34