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Invitrogen™ VPS34 Polyclonal Antibody
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Product Code. 10018943
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
10018943 100 μL 100µL
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Product Code. 10018943 Supplier Invitrogen™ Supplier No. PA146456

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Description

Rabbit Polyclonal Antibody

The target sequence has 87% sequence homology with xenopus. Suggested positive control: HepG2 whole cell lysates, antigen standard for PIK3C3 (transient overexpression lysate).

PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VPS34
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide
Gene Pik3c3
Gene Accession No. O88763, Q5D891, Q6PF93, Q8NEB9
Gene Alias 5330434F23Rik; catalytic phosphatidylinositol 3-kinase 3; catalytic subunit type 3 Antibody; class 3 phosphoinositide-3-kinase; Class III PI 3-kinase; hVps34; hVps34 Antibody; OTTMUSP00000023341; OTTMUSP00000023350; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase catalytic subunit type 3; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI3K type 3; PI-3K Vps34p; pi3kc3; PI3-kinase type 3; Pik3c3; PIK3C3 Antibody; PtdIns-3-kinase type 3; VPS34
Gene Symbols Pik3c3
Host Species Rabbit
Immunogen Synthetic peptide made to an internal portion of the human VPS34 protein (within residues 700-850).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 225326, 503700, 5289, 65052
Target Species Human, Mouse, Rat, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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