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UNC0224, MedChemExpress

Product Code. 16497007
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Product Code. 16497007 Supplier Medchem Express Supplier No. HY10929

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Description

MedChemExpress UNC0224 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 2.6 nM, an IC50 of 15 nM and a Kd of 23 nM. UNC0224 also potently inhibits b>GLP with assay-dependent IC50 values of 20-58 nM. UNC0224 is inactive against SET7/9, SET8/PreSET7, PRMT3 and JMJD2E.

UNC0224 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 2.6 nM, an IC50 of 15 nM and a Kd of 23 nM. UNC0224 also potently inhibits b>GLP with assay-dependent IC50 values of 20-58 nM. UNC0224 is inactive against SET7/9, SET8/PreSET7, PRMT3 and JMJD2E.

Specifications

Chemical Name or Material UNC0224
CAS 1197196-48-7
Color Off-White
Purity Grade Notes Research
Molecular Formula C26H43N7O2
Quantity 5 mg
Solubility Information DMSO : 16.67 mg/mL (34.32 mM; Need ultrasonic)
SMILES CN1CCC(NC2=C3C=C(OC)C(OCCCN(C)C)=CC3=NC(N4CCN(C)CCC4)=N2)CC1
Molecular Weight (g/mol) 485.67
Formula Weight 485.67
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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