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Invitrogen™ TLR7 Polyclonal Antibody
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Product Code. 10058819
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Quantity:
400 μL
Unit Size:
100µg
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Product Code. Quantity unitSize
10058819 400 μL 100µg
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Product Code. 10058819 Supplier Invitrogen™ Supplier No. PA511605

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Description

Rabbit Polyclonal Antibody

TLR7 Polyclonal Antibody for Western Blot, IHC (P)

TLR7 is a 10 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain. TLR7 plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV). TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8. TLR7 also acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response. TLR7 recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.
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Specifications

Antigen TLR7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene TLR7
Gene Accession No. P58681, Q9NYK1
Gene Alias RGD1563357; RP23-139P21.3; Tlr7; TLR7-like; toll like receptor 7; toll-like receptor 7; toll-like receptor 7-like; UNQ248/PRO285
Gene Symbols TLR7
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 98-128 amino acids from the N-terminal region of human TLR7.
Purification Method Ammonium sulfate precipitation, Size-exclusion - Dialysis
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170743, 51284
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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