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Invitrogen™ TBX1 Polyclonal Antibody

Description
TBX1 Polyclonal Antibody for Western Blot, IHC (P), IP
TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Specifications
Specifications
| Antigen | TBX1 |
| Applications | Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.25 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.1% sodium azide; pH 7.4 |
| Gene | TBX1 |
| Gene Accession No. | P70323 |
| Gene Alias | brachyury; CAFS; CATCH22; CTHM; DGCR; DGS; DORV; LOW QUALITY PROTEIN: T-box transcription factor TBX1; T-box 1; T-box 1 transcription factor C; T-box protein 1; T-box transcription factor 1; T-box transcription factor TBX1; T-box transcription factor TBX1; LOW QUALITY PROTEIN: T-box transcription factor TBX1; Tbx1; TBX1C; Testis-specific T-box protein; TGA; VCF; VCFS |
| Gene Symbols | TBX1 |
| Show More |
Product Title
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