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Invitrogen™ SUV39H2 Polyclonal Antibody

Product Code. 10058539
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Quantity:
400 μL
Unit Size:
100µg
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10058539 400 μL 100µg
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Product Code. 10058539 Supplier Invitrogen™ Supplier No. PA511366

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with non-human primate based on sequence homology.

The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59% identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUV39H2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene SUV39H2
Gene Accession No. Q9H5I1
Gene Alias 4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; FLJ23414; H3 K9 HMTase 2; H3-K9-HMTase 2; Histone H3-K9 methyltransferase 2; histone-lysine N-methyltransferase SUV39H2; KMT1; KMT1B; lysine N-methyltransferase 1B; RP11-2K17.2; Su; Su(var)3-9 homolog 2; suppressor of variegation 3-9 homolog 2; suppressor of variegation 3-9 homolog 2 (Drosophila); Suv39h histone methyltransferase; Suv39h2
Gene Symbols SUV39H2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 360-390 amino acids from the C-terminal region of human SUV39H2.
Purification Method Ammonium sulfate precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 364785, 79723
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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