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Invitrogen™ STK38 Polyclonal Antibody
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Product Code. 10008409
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Quantity:
400 μL
Unit Size:
100µg
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10008409 400 μL 100µg
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Product Code. 10008409 Supplier Invitrogen™ Supplier No. PA513831

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Description

Rabbit Polyclonal Antibody

STK38 Polyclonal Antibody for Western Blot

STK38 (also known as NDR) or Nuclear Dbf2-related protein is a serine/threonine kinase in the subgroup of the AGC kinase family that is regulated by Mob proteins. Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif. NDR acts as a novel pro-apoptotic kinase, and is a key member of the RASSF1A/MST1 signaling cascade. STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells. STK38 is incorporated into the HIV-1 particles and is cleaved by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STK38
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene STK38
Gene Accession No. Q15208
Gene Alias 5830476G13Rik; 9530097A09Rik; AA617404; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; nuclear Dbf2-related kinase 1; serine/threonine kinase 38; serine/threonine-protein kinase 38; STK38
Gene Symbols STK38
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human STK38.
Purification Method Ammonium Sulfate Precipitation, Size-exclusion - Dialysis
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11329
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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