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Invitrogen™ rRNA Monoclonal Antibody (Y10b)
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Product Code. 10170740
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Quantity:
100 μg
Unit Size:
100µg
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10170740 100 μg 100µg
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Product Code. 10170740 Supplier Invitrogen™ Supplier No. MA113017

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Description

Mouse Monoclonal Antibody

This clone recognizes both the large and the small subunit of rRNA from all eukaryotic cells. MA1-13017 has been successfully used in Immunocytochemistry, immunoprecipitation, immunofluorescence applications. The MA1-13017 immunogen is from whole ribosomal rRNA 52.8S.

rRNA (ribosomal RNA) forms a major structural component of ribosomes which provides a mechanism for decoding mRNA information into amino acids/proteins through the process of translation. rRNA plays a key role in accurate positioning of mRNA as well as peptidyl tRNA, and also plays a structural role in peptidyl transferase activity by generating scaffolds where ribosomal proteins are assembled. rRNA is generated inside nucleolus, which is localized in nucleus of the cells and contains genes essential for encoding rRNA. Defective rRNA may implicate in certain pathologies, for example: decreased rRNA expression has been observed in subjects with myelodysplastic syndromes, and abnormal rRNA expression has also been linked to Alzheimer's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen rRNA
Applications Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone Y10b
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Alias ribosomal RNA; rRNA
Host Species Mouse
Immunogen Whole ribosomal rRNA 5.8S.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Multi-species
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG3 κ
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