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PI4K2A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA515275

Code : LE

Additional Details : Weight : 0.01000kg

Product Code. 10079079

  • £436.00 / 100µg
Estimated Shipment: 09-08-2024
to see stock.

Description

Description

PI4K2A (PI4K2 alpha) lipid kinase or phosphatidylinositol 4-kinase type 2 alpha is involved in the formation of phosphatidylinositolpolyphosphates (PtdInsPs) which are centrally involved in many biologic processes ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4K2A phosphorylates PtdIns at the D-4 position which is an essential step in the biosynthesis of PtdInsPs. PI4K2A is a novel regulator of tumor growth by its action on angiogenesis and HIF-1alpha regulation. PI4K2A generates PtdIns4P-rich domains within the Golgi which regulate targeting of clathrin adaptor AP-1 complexes. PI4K2A is also required for Wnt to regulate LRP6 phosphorylation.
Specifications

Specifications

PI4K2A
Polyclonal
Unconjugated
Pi4k2a
55 kDa type II phosphatidylinositol 4-kinase; null; phosphatidylinositol 4-kinase; phosphatidylinositol 4-kinase type 2 alpha; phosphatidylinositol 4-kinase type 2-alpha; phosphatidylinositol 4-kinase type II; phosphatidylinositol 4-kinase type II (PI4KII); phosphatidylinositol 4-kinase type II-alpha; Pi4k2; PI4K2A; Pi4kii; PIK42A
Rabbit
Protein G
RUO
55361, 84095
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
2 mg/mL
PBS with 0.09% sodium azide
Q2TBE6, Q9BTU6
Pi4k2a
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PI4K2A (PI4K II)
400 μL
Primary
Human, Mouse
Antibody
Ig
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