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Invitrogen™ Phospho-STAT5 beta (Tyr694) Monoclonal Antibody (ST5P-4A9)
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Product Code. 10159682
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10159682 50 μg Each
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10159682 Supplier Invitrogen™ Supplier No. 336000

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Mouse Monoclonal Antibody

Phospho-STAT5 beta (Tyr694) Monoclonal Antibody for Western Blot, ELISA

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
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Specifications

Antigen Phospho-STAT5 beta (Tyr694)
Applications ELISA, Western Blot
Classification Monoclonal
Clone ST5P-4A9
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene Stat5b
Gene Accession No. P42232, P51692, P52632, Q9TUM3
Gene Alias LOC101122961; mammary gland factor STAT5B; Signal transducer and activator of transcription 5a; signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; STAT5B; transcription factor STAT5B
Gene Symbols Stat5b
Host Species Mouse
Immunogen A synthetic tyrosine phosphorylated peptide encompassing the conserved C-terminal tyrosine phosphorylation site (Y694) of murine STAT5. This peptide is conserved in human, bovine, sheep, and rat STAT5 proteins.
Purification Method Affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101122961, 20851, 25126, 282376, 6777
Target Species Human, Mouse, Rat, Bovine, Sheep
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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