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Invitrogen™ Phospho-LAT (Tyr132) Polyclonal Antibody
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Product Code. 10088092
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10088092 Supplier Invitrogen™ Supplier No. 44224

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Rabbit Polyclonal Antibody

Phospho-LAT (Tyr132) Polyclonal Antibody for Western Blot

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-LAT (Tyr132)
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene LAT
Gene Accession No. O43561
Gene Alias 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36
Gene Symbols LAT
Host Species Rabbit
Immunogen The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human LAT that contains tyrosine 132.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27040
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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