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Invitrogen™ Phospho-Cofilin (Ser3) Polyclonal Antibody

Description
Phospho-Cofilin (Ser3) Polyclonal Antibody for ICC/IF, Western Blot
Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
Specifications
Specifications
| Antigen | Phospho-Cofilin (Ser3) |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Formulation | Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3 |
| Gene | CFL1 |
| Gene Accession No. | P18760, P23528, P45592 |
| Gene Alias | 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18 |
| Gene Symbols | CFL1 |
| Host Species | Rabbit |
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Product Title
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