Paritaprevir, MedChemExpress

Product Code.	Quantity	unitSize
16491467	50 mg	50mg
16485258	10 mg	10mg
16447977	5 mg	5mg
16435926	100 mg	100mg

Product Code. 16491467 Supplier Medchem Express Supplier No. HY12594

Description

MedChemExpress Paritaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 μM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor).

Paritaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 μM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor).

Specifications

• Chemical Name or Material: Paritaprevir
• CAS: 1216941-48-8
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₄₀H₄₃N₇O₇S
• Quantity: 50 mg
• Synonym: ABT-450 Veruprevir
• Solubility Information: DMSO : ≥ 125 mg/mL (163.21 mM) ∣H2O : ≥ 0.1 mg/mL (0.13 mM)
• SMILES: O=C([C@]1(NC([C@@]2([H])N3C[C@H](OC4=C(C=CC=C5)C5=C6C(C=CC=C6)=N4)C2)=O)[C@H](/C=C\CCCCC[C@H](NC(C7=NC=C(C)N=C7)=O)C3=O)C1)NS(=O)(C8CC8)=O
• Molecular Weight (g/mol): 765.88
• Formula Weight: 765.88
• Percent Purity: 98.0%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): COVID-19-anti-virus

Research purposes only