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Invitrogen™ PAPPA Monoclonal Antibody (10E2)

Product Code. 10158813
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Quantity:
100 μg
Unit Size:
100µg
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10158813 100 μg 100µg
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Product Code. 10158813 Supplier Invitrogen™ Supplier No. MA122743

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Description

Mouse Monoclonal Antibody

MA1-22743 detects PAPP A in Human samples.

Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAPPA
Applications ELISA, Western Blot
Classification Monoclonal
Clone 10E2
Concentration 5.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene PAPPA
Gene Accession No. Q13219
Gene Alias 8430414N03Rik; ASBABP2; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; DIPLA1; IGFBP-4 ase; IGFBP-4ase; IGF-dependent IGFBP-4 protease; insulin-like growth factor-dependent IGF binding protein-4 protease; insulin-like growth factor-dependent IGF-binding protein 4 protease; PAG1; PAPA; PAPP A; PAPPA; PAPP-A; PAPPA1; Pappalysin; pappalysin 1; pappalysin-1; pregnacy-associated plasma protein A; pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
Gene Symbols PAPPA
Host Species Mouse
Immunogen Purified human PAPP-A antigen.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5069
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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